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Table 3 Description of total annual costs by perspective

From: Economic burden of secondary progressive multiple sclerosis: DISCOVER study

Variable

NHS perspective

PwSPMS’ perspective

Societal perspective

Annual direct health care costs (€). Mean (SD)

 - DMT

6,435.90 (7,027.76)

0.32 (2.47)

6,436.21 (7,027.50)

 - Other treatments

1,517.84 (1,664.82)

101.33 (343.90)

1,619.17 (1,845.28)

 - Medical visits

829.50 (617.98)

110.09 (493.67)

939.59 (786.16)

 - Specific attention (daycare/rehabilitation)

435.70 (2,627.92)

987.92 (4257.15)

1423.62 (4915.84)

 - Hospital admissions

307.49 (2,429.37)

9.10 (156.82)

316.59 (2433.28)

 - Emergency room visits

19.09 (143.98)

0.00 (0.00)

19.09 (143.98)

 - Other costs (Tests)

561.87 (553.81)

14.73 (128.89)

576.60 (556.20)

Total costs

10,119.67 (8,576.25)

1,223.49 (4,471.58)

11,343.16 (9,519.40)

Annual direct non-health care costs (€). Mean (SD)

 - Support and adaptation devices at home/vehicle

264.28 (767.10)

6,200.84 (2,5687.02)

6,465.12 (2,5677.34)

 - Support for domestic/housekeeping tasks

136.69 (848.65)

816.86 (2,188.18)

953.56 (2,310.81)

 - Support for daily tasks (paid/unpaid caregiver)

859.51 (8,345.12)

386.42 (1,828.80)

1,245.93 (8,711.34)

 - Other costs (transport)

40.21 (325.90)

70.52 (137.71)

110.73 (34.36)

Total cost

1,300.69 (8,520.16)

7,474.65 (2,6276.65)

8,775.34 (2,7810.01)

Annual indirect costs (€). Mean (SD)

 - PwSPMS work disability due to SPMS/MS

-

-

13,371.87 (11,349.50)

 - PwSPMS sick leave due to SPMS/MS

-

-

137.03 (1,706.01)

 - PwSPMS unemployment due to SPMS/MS

-

-

139.46 (1,195.60)

 - Reduction of working hours due to SPMS/MS

-

-

287.07 (1,879.70)

 - Early retirement due to SPMS/MS

-

-

2,501.65 (7,398.57)

 - PwSPMS absenteeism due to SPMS/MS

-

-

39.74 (211.87)

 - PwSPMS presenteeism due to SPMS/MS

-

-

6.43 (23.69)

 - PwSPMS loss of leisure time

-

-

1793.86 (2,605.51)

 - Work termination of unpaid caregiver

-

-

1,492.68 (4,667.94)

 - Unpaid caregiver reduction of working hours

-

-

97.35 (578.78)

 - Unpaid caregiver absenteeism

-

-

232.04 (707.59)

 - Unpaid caregiver loss of leisure time

-

-

1,400.23 (2,560.84)

Total costs

-

-

21,362.37 (12,769.34)

Total annual costs (€). Mean (SD)

11,420.36 (12,502.82)

8,698.14 (26,541.37)

41,480.87 (31,668.28)

  1. DMT disease-modifying treatments, MS multiple sclerosis, NHS National Health System, pwSPMS people with progressive multiple sclerosis, SD standard deviation