Table 4 Immunosuppression according to original vs. generic packs (total 2017–2021)
From: A population-based analysis of immunosuppression therapy after organ transplantation
Bavaria, outpatients | Nationwide, in- and outpatients | |||
|---|---|---|---|---|
Original Packs, n (%) | Generic/Biosimilar, n (%) | Original Packs, n (%) | Generic/Biosimilar, n (%) | |
Glucocorticoids | 2,738 (4.5) | 58,281 (95.5) | 5,833 (6.7) | 81,432 (93.3) |
Prednisolone | 1,848 (3.6) | 48,932 (96.4) | 3,177 (5.0) | 59,752 (95.0) |
Prednisone | 547 (9.6) | 5,163 (90.4) | 1,278 (10.6) | 10,797 (89.4) |
Methylprednisolone | 311 (14.1) | 1,902 (85.9) | 1,347 (14.0) | 8,249 (86.0) |
Dexamethasone | 11 (0.5) | 2,284 (99.5) | 29 (1.1) | 2,634 (98.9) |
Cloprednol | 11 (100) | 0 (0) | 2 (100.0) | 0 (0.0) |
Mycophenolic acid | 109,159 (81.6) | 24,588 (18.4) | 103,477 (78.8) | 27,839 (21.2) |
mTOR inhibitors | 37,805 (100) | 0 (0) | 49,211 (100.0) | 0 (0.0) |
Everolimus | 27,905 (100) | 0 (0) | 40,718 (100.0) | 0 (0.0) |
Sirolimus | 9,900 (100) | 0 (0) | 8,493 (100.0) | 0 (0.0) |
Calcineurin Inhibitors | 325,624 (93.3) | 23,278 (6.7) | 353,161 (92.4) | 28,855 (7.6) |
Tacrolimus | 237,863 (92.7) | 18,759 (7.3) | 238,638 (91.4) | 22,347 (8.6) |
Ciclosporin | 87,761 (95.0) | 4,619 (5.0) | 114,523 (94.6) | 6,508 (5.4) |
Azathioprine | 763 (9.9) | 6,982 (90.1) | 1,066 (13.1) | 7,079 (86.9) |
Belatacept | 2,688 (100) | 0 (0) | 4,358 (100.0) | 0 (0.0) |