Skip to main content

Table 2 Generic introductions of antiretroviral drugs in the Netherlands, with lowest pharmacy purchase price (€)

From: Impact of generic antiretroviral drugs introduction on pharmaceutical expenditure patterns in the Netherlands: a six-year retrospective database analysis from 2016 to 2022

 

Year

2016

PPP** (€)

2017

PPP** (€)

2018

PPP** (€)

2019

PPP** (€)

2020

PPP** (€)

2021

PPP** (€)

2022

PPP** (€)

Antiretroviral substance

 Antivirals for treatment of HIV infections, combinations

  Abacavir/lamivudine (ABC/3TC)

434.50

346.00

69.95

38.25

23.95

23.95

19.95

  Tenofovir disoproxil/emtricitabine (TDF/FTC)

526.56

378.52

47.50

28.12

28.12

28.12

28.12

  Tenofovir disoproxil/emtricitabine/efavirenz (TDF/FTC/EFV)

791.35

745.55

467.00

467.00

40.80

40.80

36.72

 Protease inhibitors

  Atazanavir (ATZ) *

436.79

427.47

423.01

408.32

385.50

254.19

254.10

  Darunavir (DRV) *

447.00

434.69

432.70

50.40

43.25

43.25

43.25

  Ritonavir (RTV)

342.79

25.58

21.62

21.62

21.62

21.62

21.62

 Nucleoside and nucleotide reverse transcriptase inhibitors

  Abacavir (ABC)

257.20

249.95

245.71

207.40

207.40

194.31

207.40

  Tenofovir disoproxil (TDF)

322.23

231.27

35.24

17.75

17.75

12.95

12.89

 Non-nucleoside reverse transcriptase inhibitors

  Nevirapine (NVP)

202.47

159.98

42.16

42.16

34.85

34.85

29.50

  1. * calculated with a defined daily dose of atazanavir of 300 mg and darunavir of 800 mg
  2. ** pharmacy purchase price (PPP)