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Table 2 Scoping review studies investigating urban-rural disparities in the quality of healthcare in Japan

From: Rural and urban disparities in access and quality of healthcare in the Japanese healthcare system: a scoping review

Title

Year of publication

Language

Study design

Study setting: Level of care

Study setting: national/prefecture/city, town, village

Data source

Sample size

A regional difference in care burden feelings of family caregivers with frail elderly using visiting nurse [30]

2007

Japanese

Cross-sectional

Home-visit nursing service

One prefecture

Questionnaire

167 families

Current situations and issues in respiratory medicine in Japan [31]

2010

English

Cross-sectional

Hospital

National

Questionnaire

1251 hospitals

Geographic distribution of radiologists and utilization of teleradiology in Japan: A longitudinal analysis based on national census data [32]

2015

English

Cross-sectional

Municipality

National

Questionnaire

1811 municipalities

Rural-urban disparity in emergency care for acute myocardial infarction in Japan [33]

2018

English

Prospective cohort

hospital

Prefecture

Registry

Rural: 1313 individuals、Metropolitan: 2,075 individuals

Geographical distribution of family physicians in Japan: a nationwide cross-sectional study [34

2019

English

Cross-sectional

Prefecture

National

Database of academic society

527 family physicians

Geography of suicide in Japan: spatial patterning and rural-urban differences [35]

2021

English

Cross-sectional

Municipality

National

Suicide database

240673 individuals

Regional and facility disparities in androgen deprivation therapy for prostate cancer from a multi-institutional Japan-wide database [36]

2021

English

Prospective cohort

Hospital

National

Japan Study Group of Prostate Cancer (J-CaP)

19162 individuals

Differences in treatment and survival between elderly patients with thoracic esophageal cancer in metropolitan areas and other areas [37]

2021

English

Retrospective cohort

Prefecture

National

The national database of hospital-based cancer registries

5066 individuals

Regional disparities in adherence to guidelines for the treatment of chronic heart failure [38]

2021

English

Prospective cohort

Hospital

Prefecture

Acute Decompensated Heart Failure Syndromes (ATTEND)

387 individuals

Urban-rural inequalities in care and outcomes of severe traumatic brain injury: A nationwide inpatient database analysis in Japan [39]

2022

English

Retrospective cohort

Hospital

National

Diagnosis Procedure Combination(DPC)

48910 individuals

Regional variation in national healthcare expenditure and health system performance in central cities and suburbs in Japan [40]

2022

English

Cross-sectional

Municipality

National

Open data

23 urban municipalities and 27 rural municipalities

Disparity of performance measure by door-to-balloon time between a rural and urban area for management of patients with ST-segment elevation myocardial infarction - insights from the Nationwide Japan Acute Myocardial Infarction Registry [41]

2023

English

Retrospective cohort

Hospital

National

The Japan Acute Myocardial Infarction Registry (JAMIR)

17167 individuals

The inter-prefectural regional disparity of healthcare resources and representative surgical procedures in orthopedics and general surgery: a nationwide study in Japan during 2015–2019 [42]

2023

English

Cross-sectional

Prefecture

National

Nippon Data Base (NDB) Open data

47 prefectures

Development and validation of a rurality index for healthcare research in Japan: a modified Delphi study [43]

2023

English

Cross-sectional

Municipality

National

Open data

335 secondary medical areas and 1713 municipalities

Primary care physicians working in rural areas provide a broader scope of practice: a cross‑sectional study [44]

2024

English

Cross-sectional

Primary care clinic and hospital

National

Questionnaire

299 primary care physicians

Title

Index or definition of rurality

Details of the index or definition of rurality: population size/density

Donabedian's model (structure, process, outcomes)

Study outcome

Covariates

Overview of results

A regional difference in care burden feelings of family caregivers with frail elderly using visiting nurse [30]

Urban: ordinance, designated cityRural: depopulated area

Not applicable

Outcomes

Care burden of family caregivers

Caregiver's age Caregiver's gender Duration of care Welfare services used Certification for long-term care/support needs, Activities of daily living

No difference in care burden of family caregivers

Current situations and issues in respiratory medicine in Japan [31]

Population size

Metropolitan areas (population ≥500000)Urban areas (200000 to 500000)Provincial areas (50000 to 200000)Rural areas (<50000)

Structure, process

Numbers of internists, respiratory physicians, respiratory specialistsScope of practice

Not applicable

Fewer respiratory specialists in rural areas than the Japanese average. Lower self-containment level (Scope of Practice) in rural areas  than in urban areas.

Geographic distribution of radiologists and utilization of teleradiology in Japan: A longitudinal analysis based on national census data [32]

Ordinance designated city/special ward/city/town

Not applicable

Structure

Numbers of radiologists, computed tomography and magnetic resonance imaging

Not applicable

Fewer radiologists in rural areas than in urban areas.

Rural-urban disparity in emergency care for acute myocardial infarction in Japan [33]

Population size

Rural areas: prefecture with population <2 million

Process

Direct ambulance transport, onset-to-balloon time

Age, sex, mode of transport, hypertension, diabetes mellitus, dyslipidemia, current smoker, previous percutaneous coronary intervention, previous myocardial infarction, Killip classification at presentation, ST elevation myocardial infarction, multivessel disease and left anterior descending coronary artery lesion as the culprit

Less direct ambulance transportation in rural areas than in urban areas. Onset-to-balloon time in rural areas is longer than in urban areas.

Geographical distribution of family physicians in Japan: a nationwide cross-sectional study [34]

Population densityOrdinance designated City/special ward/town

Municipalities divided into quintiles by population density

Structure

Number of family physicians per 100000 population

Not applicable

More family physicians in rural areas than any other specialists.

Geography of suicide in Japan: spatial patterning and rural-urban differences [35]

Population density

Municipalities divided into deciles sorted by population density

Outcomes

Number of suicides

Single-person households Unmarried adultsUnemployment rateEducational attainment

Men aged 0–39 and 40–59 years: rural residents had a higher suicide risk than urban residents.

Regional and facility disparities in androgen deprivation therapy for prostate cancer from a multi-institutional Japan-wide database [36]

Population density

Urban areas: prefectures with a population density >1000 persons/km2

Outcomes

Cancer mortality All-cause mortality

Age, initial Prostate-Specific Antigen (PSA) value at pretreatmentGleason scoreClinical TNM-stageTherapeutic modality Regional area or facility type

Geographical regions (rural or urban) do not affect outcomes

Differences in treatment and survival between elderly patients with thoracic esophageal cancer in metropolitan areas and other areas [37]

Population size

Urban areas: a prefecture with >6 million population

Process, outcomes

Treatment strategy, mortality

Age, sex, first-line treatments

cStage I thoracic esophageal cancer mortality in rural areas is worse than in urban areas.

Regional disparities in adherence to guidelines for the treatment of chronic heart failure [38]

Authors-defined rural and urban areas

 

Process

Treatment rates for heart failure with reduced ejection fraction (HFrEF) as recommended by guidelines

Not applicable

Treatment rates for HFrEF following guidelines were lower in rural areas than in urban areas.

Urban-rural inequalities in care and outcomes of severe traumatic brain injury: A nationwide inpatient database analysis in Japan [39]

Population size

Urban areas (population ≥50000)Rural areas (10000 to 50000)

Outcomes

In-hospital mortality

Age, sex, fiscal year, and season of admission, admission on weekends or at night, referral from other institutions, ambulance use, smoking history, body mass index, comorbidities, Charlson comorbidity index, Japan Coma Scale score at admission, details of head injury (diffuse axonal injury, acute epidural hemorrhage, acute subdural hemorrhage, traumatic subarachnoid hemorrhage, contusion, skull fracture, penetrating injury), and injury severity score

Mortality by brain traumatic injury in rural areas is greater than that in urban areas.

Regional variation in national healthcare expenditure and health system performance in central cities and suburbs in Japan [40]

Population size

Metropolitan areas (population ≥500000)Suburb areas: three categories (100000 to 500000, 30000 to 100000, <30000)

Structure, process, outcomes

Total medical expenses of national healthcare experience: medical expenses of inpatients, medical expenses of outpatients, and consultation rates of inpatients and outpatients

Number of doctors, number of nurses, number of beds, income, number of people employed in primary industries, percentage of completely unemployed, percentage of population aged 65–74, number of household members, percentage of singles, percentage of households with own houses

The factors affecting medical care costs in suburban areas differ from those in metropolitan areas.

Disparity of performance measure by door-to-balloon time between a rural and urban area for management of patients with ST-segment elevation myocardial infarction - Insights from the Nationwide Japan Acute Myocardial Infarction Registry [41]

Population density

Municipalities divided by the median of population density

Process, outcomes

In-hospital death, door-to-balloon time

 

Both in-hospital death and door-to-balloon time are worse in rural areas than in urban areas.

The inter-prefectural regional disparity of healthcare resources and representative surgical procedures in orthopedics and general surgery: a nationwide study in Japan during 2015–2019 [42]

Population size and density

Urban areas: large cities with a population >500000 and top seven prefectures with a high population density >1000 persons/km2.

Structure, process

Numbers of physicians and surgeries

Not applicable

Nonlarge cities had significantly more femur fracture surgeries, lower leg fracture surgeries, total knee arthroplasties, cholecystectomies, and hospitals than in large cities. Sparsely populated areas had significantly more femur fracture surgeries, lower leg fracture surgeries, total knee arthroplasties, cholecystectomies, orthopedic surgeon specialists, hospitals, and higher aging rates than densely populated areas.

Development and validation of a rurality index for healthcare research in Japan: a modified Delphi study [43]

Rurality index for Japan

 

Structure, outcomes

Indices for physician distribution and average life expectancy

Not applicable

The indices for physician distribution and average life expectancy are negatively correlated with rurality.

Primary care physicians working in rural areas provide a broader scope of practice: a cross‑sectional study [44]

Rurality index for Japan

 

Process

Scope of practice

Sex, years of clinical experience, clinical setting (clinic or hospital), certification status, and experience of practice in rural areas

The scope of practice is broader in rural areas than in urban areas.